The U.S. Department of Energy (DOE) has entered into collaboration agreements with 24 organizations to support the Genesis Mission, a national initiative focused on harnessing artificial intelligence (AI) for discovery science, national security, and energy innovation.
The announcement follows President Trump’s Executive Order on Removing Barriers to American Leadership in Artificial Intelligence and aligns with his America’s AI Action Plan introduced earlier this year. The plan aims to eliminate obstacles to innovation, decrease reliance on foreign sources, and strengthen domestic scientific capabilities.
A White House meeting brought together industry representatives, U.S. Secretary of Energy Chris Wright, DOE Under Secretary for Science and Genesis Mission Director Dr. DarĂo Gil, and Michael Kratsios, Director of the White House Office of Science and Technology Policy. The event marked the launch of public-private partnerships in AI intended to create scalable national infrastructure for advanced scientific research.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
“Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation,” said DOE Under Secretary for Science and Genesis Mission Director Dr. DarĂo Gil. “These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The organizations involved have signed memorandums of understanding after responding either to a request for information from DOE or through active projects with DOE or its National Laboratories related to Genesis Mission activities. Products developed as part of this mission are intended to be architecture-agnostic.
Participants include major technology firms such as Accenture; AMD; Anthropic; Armada; Amazon Web Services; Cerebras; CoreWeave; Dell; DrivenData; Google; Groq; Hewlett Packard Enterprise; IBM; Intel; Microsoft; NVIDIA; OpenAI; Oracle; Periodic Labs; Palantir; Project Prometheus; Radical AI; xAI; and XPRIZE.
DOE plans additional meetings with private sector partners as well as academic institutions and philanthropic organizations in order to expand collaboration opportunities further. The department continues accepting submissions through open requests for information regarding transformational AI models (open until January 14th) and capabilities relevant for national security (open until January 23rd). More details can be found at www.genesis.energy.gov.



