President Trump has announced the launch of the Genesis Mission, a new initiative led by the Department of Energy (DOE) that aims to use artificial intelligence (AI) and advanced computing to double the productivity and impact of American science and engineering over the next decade. The mission is intended to secure U.S. energy leadership, accelerate scientific discovery, and bolster national security.
The Genesis Mission will connect supercomputers, AI systems, quantum technologies, and scientific instruments from across DOE’s 17 National Laboratories as well as partners in industry and academia. According to the DOE, this integrated platform will be the most complex and powerful scientific instrument ever built in the United States. It will bring together about 40,000 scientists, engineers, and technical staff with private sector innovators.
U.S. Secretary of Energy Chris Wright stated: “Throughout history, from the Manhattan Project to the Apollo mission, our nation’s brightest minds and industries have answered the call when their nation needed them. Today, the United States is calling on them once again. Under President Trump’s leadership, the Genesis Mission will unleash the full power of our National Laboratories, supercomputers, and data resources to ensure that America is the global leader in artificial intelligence and to usher in a new golden era of American discovery.”
The effort builds on previous executive actions aimed at reducing barriers to AI innovation in America. The Genesis Mission will focus on three main challenges: accelerating advanced nuclear technologies and grid modernization for energy security; supporting discovery science through investments in quantum computing; and developing advanced AI for national security applications.
Secretary Wright has appointed Dr. Darío Gil, Under Secretary for Science at DOE, as director of the initiative.
Dr. Darío Gil said: “The Genesis Mission marks a defining moment for the next era of American science. We are linking the nation’s most advanced facilities, data, and computing into one closed-loop system to create a scientific instrument for the ages, an engine for discovery that doubles R&D productivity and solves challenges once thought impossible.”
Brandon Williams, Administrator of the National Nuclear Security Administration (NNSA), added: “The Genesis Mission represents the next great chapter and an unparallelled opportunity for America’s scientific and national security leadership.
Building on decades of innovation and collaboration across our national laboratories, NNSA will leverage AI, quantum computing, and advanced data analytics that will strengthen our deterrents and ensure the United States maintains an unmatched strategic edge over our adversaries. Under President Trump’s leadership, this mission will embody the very best of American ingenuity, turning science and innovation into security.”
Dr. John Wagner, Chair of DOE’s National Laboratory Directors’ Council commented: “DOE’s National Laboratories are engines of discovery that keep the United States competitive and secure. The Genesis Mission unlocks the full potential of these institutions by giving our scientists and engineers tools to work at the speed of innovation. Our laboratories have always risen to meet the nation’s greatest challenges, and this initiative ensures we continue that legacy in the age of artificial intelligence.”


